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April 3rd, 2017, 01:04 PM
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Join Date: Mar 2012
Re: Free Study Material For CSIR-UGC Net

CSIR UGC NET is an OMR paper-pen based test directed by the Council of Scientific and Industrial Research (CSIR) to decide the eligibility of indian national aspirants for award of Junior Research Fellowship (JRF) NET and for ascertaining the appointment of lecturers (NET) in the following subject areas under the faculty of Science and Technology.

Examination Pattern :

Subject -


(i) Life Sciences
(ii) Earth, Atmospheric, Ocean and Planetary Sciences
(iii) Mathematical Sciences
(iv) Chemical Sciences
(v) Physical Sciences

Marks - 200

Duration:- 3 hrs

Session:-

Morning Session 9.00AM-12.00 Noon
Afternoon Session 2.00 PM-5.00 PM

Syllabus of the Life Science

1. MOLECULES AND THEIR INTERACTION RELAVENT TO BIOLOGY

A. Structure of atoms, molecules and chemical bonds.
B. Composition, structure and function of biomolecules (carbohydrates, lipids,
proteins, nucleic acids and vitamins).
C. Stablizing interactions (Van der Waals, electrostatic, hydrogen bonding,
hydrophobic interaction, etc.).
D. Principles of biophysical chemistry (pH, buffer, reaction kinetics,
thermodynamics, colligative properties).
E. Bioenergetics, glycolysis, oxidativephosphorylation, coupled reaction, group
transfer, biological energy transducers.
F. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation,
mechanism of enzyme catalysis, isozymes.
G. Conformation of proteins (Ramachandran plot, secondary, tertiary and quaternary
structure; domains; motif and folds).
H. Conformation of nucleic acids (A-,B-, Z-,DNA), t-RNA, micro-RNA).
I. Stability of protein and nucleic acid structures.
J. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.

2. CELLULAR ORGANIZATION

A. Membrane structure and function: Structure of model membrane, lipid bilayer
and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps,
mechanism of sorting and regulation of intracellular transport, electrical properties of membranes.


B. Structural organization and function of intracellular organelles: Cell wall, nucleus,
mitochondria, Golgi bodies, lysosomes, endoplasmic reticulum, peroxisomes, plastids,
vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility.


C. Organization of genes and chromosomes: Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and repetitive DNA, heterochromatin, euchromatin, transposons.

D. Cell division and cell cycle:Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.

E. Microbial Physiology: Growth, yield and characteristics, strategies of cell division,
stress response.

3. FUNDAMENTAL PROCESSES
A. DNA replication, repair and recombination: Unit of replication, enzymes involved, replication origin and replication fork, fidelity of replication, extrachromosomal replicons, DNA damage and repair mechanisms.


B. RNA synthesis and processing: Transcription factors and machinery, formation of
initiation complex, transcription activators and repressors, RNA polymerases, capping, elongation and termination, RNA processing, RNA editing, splicing, polyadenylation, structure and function of different types of RNA, RNA transport.


C. Protein synthesis and processing: Ribosome, formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, translational proof-reading, translational inhibitors, post- translational modification of proteins.

D. Control of gene expression at transcription and translation level: Regulation of
phages, viruses, prokaryotic and eukaryoticgene expression, role of chromatin in
regulating gene expression and gene silencing.


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