Here I am providing syllabus of GAT Entrance Exam conducted by GITAM University for admission in M.Pharmacy Course for your reference:

GITAM University GAT (M.Pharmacy) Entrance Exam Syllabus

Section A: PHARMACEUTICS
1. Physical Pharmacy: States of mater, Physical properties of drug molecules, pH, buffers and isotonic solution, solubility phenomena, surface tension, interfacial phenomenon, Kinetics, Rheology, Micromeretics & powder flow, Diffusion and dissolution, Colloids, Complexation and protein binding.

2. Pharmaceutical Engineering: Stoichiometry, Fluid Flow, Heat Transfer, Evaporation, Distillation, Drying, Size Reduction, Size Separation, Mixing, Material Handling System, Filtration & Centrifugation, Crystallization, humidification, air conditioning and refrigeration, Material of Plant Construction, Corrosion and Plant lay out.

3. Pharmacy Practice: Professional Pharmacy, Pharmaceutical jurisprudence including Drugs and Cosmetics Act 1940 and rules 1945. Pharmacy Act 1948, Code of Pharmaceutical ethics. Prescription: definition, various parts of prescription and their functions, handling of prescription, sources of errors, care required in dispensing procedures including labeling of dispensed products, preliminary knowledge of
important Latin terms used in the prescriptions and their translation in to English. Posology: Definition, Factors affecting dose selection. Calculation of children and infant doses.

4. Pharmaceutical Technology: Principles, Formulation, Ingredients, method of
manufacture, evaluation, quality control tests, labeling and packaging of following class of product:
Solid dosage forms- Tablets, coating, capsules, microcapsules, powders, granules etc.
Liquid dosage forms- solutions, suspensions, emulsions, Semisolid dosage forms- ointment, creams, gels, suppositories, Parenterals- injections small volume, large volume, ophthalmic preparations and Pre-formulation studies, Stability studies and Pharmacopoeal specifications for various formulations.
Formulation of cosmetics preparation like lipstick, shampoo, creams, nail preparations
and dentifrices, powers etc.

5. Biological Pharmacy and Pharmaceutical Biotechnology: Principles and methods of microbiological assays of the Pharmacopoeia. Methods of preparation of official sera and vaccines. Serological and diagnostics tests. Applications of microorganisms in bio conversions and in pharmaceutical industry.

6. Biopharmaceutics and Pharmacokinetics and their importance in formulation. Introduction to biopharmaceutics: Drug absorption, distribution, metabolism and elimination. Compartment model- Definition and Scope. Pharmacokinetics of drug absorption - Zero order and first order absorption rate constant. Determination of pharmacokinetic parameters.

Bioavailability and bioequivalence: Measures of bioavailability, Cmax, tmax, Kel and Area Under the Curve (AUC); Review of regulatory requirements for conducting bioequivalent studies. Biopharmaceutical Classification System (BCS) of drugs.

Section B: PHARMACEUTICAL ANALYSIS AND QUALITY ASSURANCE
1. Fundamental of pharmaceutical analysis, Theoretical consideration and application in drug analysis and quality control.
Acid base titrations: Acid base concepts, ionization, law of mass action, common ion
effect, ionic product of water, pH, hydrolysis of salts, Henderson- Hasselbach equation, buffer solutions, neutralization curves, acid-base indicators, theory of indicators, choice of indicators, mixed indicators, polyprotic systems, polyamine and amino acid systems, amino acid titrations.
Oxidation- Reduction titrations: Concepts of oxidation and reduction, theory, redox
indicators, oxidation-reduction curves, iodometry, Precipitation titrations: Principles,
procedures of Precipitation reactions.
Complexometric titrations: Complexing agents used as titrants, indicators, types of
complexometric titrations, masking and demasking;
Non-aqueous titrations: Acidic and basic drugs, solvents used, indicators
Gravimetry: Precipitation techniques, colloidal state, supersaturation, co-precipitation,
post- precipitation, digestion, washing of the precipitate, thermogravimetric curves.
Miscellaneous Methods of Analysis: Diazotization titrations, Kjeldahl method of nitrogen estimation, Karl-Fischer aquametry, oxygen flask combustion method, gasometry.
Potentiometry: Electric potential, electrochemical cell, reference electrodes, indicator
electrodes, measurement of potential and pH, construction and working of electrodes,
potentiometric titrations, method of deduction of end-point.
Conductometry: Conductance, conductivity cell, conductometric titrations, applications.
Polarography: Instrumentation, DME, residual current, diffusion current and limiting current, polarographic wave, Ilkovic’s equation, effect of oxygen on polarographic wave, polarographic maxima and suppressors, applications.
Amperometry: Introduction, types of electrodes used, reference and indicator electrode, instrumentation, titration procedure, advantages and disadvantages of amperometry over potentiometry, pharma applications.

Attached Files

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