Guanidine Hydrochloride is the strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can be solubilize insoluble or denatured proteins such as inclusion bodies. This can be utilized as the first step in refolding proteins or enzymes into their active form. Urea as well as Dithiothreitol (DTT) may also be necessary.

Properties

Related Categories Biochemicals and Reagents, Chaotropic Agents, Core Bioreagents, Denaturation, Nucleosides and Nucleotides,

InChI Key
PJJJBBJSCAKJQF-UHFFFAOYSA-N

Assay
≥98%

Contains
≤0.4% SiO2 as anticaking agent

pH
(25 °C, 4.6 - 6/573 g/L)

MP
180-185 °C(lit.)

Solubility
H2O: soluble573 g/L at 20 °C (completely)

Safety Information

Symbol



Signal word
Warning

Hazard statements
H302 + H332-H315-H319

Precautionary statements
P261-P280-P301 + P312 + P330-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves

RIDADR
NONH for all modes of transport

WGK Germany
1

RTECS
MF4300000

Please find the file attached below which has the details of the Material Safety Data Sheet of Guanidine hydrochloride

Attached Files

Guanidine hydrochloride MSDS.pdf (47.6 KB, 98 views)