#1
June 22nd, 2016, 10:58 AM
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Lurasidone HCL
Hello sir I want to know about uses of Lurasidone HCL so here can you please give me its basic information ?
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#2
June 22nd, 2016, 11:47 AM
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Re: Lurasidone HCL
Hey as per your demand here I am providing you details of uses of Lurasidone HCL About Lurasidone HCL Lurasidone is FDA approved for the treatment of schizophrenia since 2010 and depressive episodes associated with bipolar I disorder since 2013 It received regulatory approval in the UK in September 2014. Uses of Lurasidone HCL The use of lurasidone in pregnant women has not been studied and is not recommended, although it should be noted that it is a category B drug Excretion in breast milk is also unknown; lurasidone is not recommended for breastfeeding women In the United States it is not indicated for use in children Side effects Side effects are generally similar to other antipsychotics. The drug has a relatively well-tolerated side effect profile, with low propensity for QTc interval changes, weight and lipid-related adverse effects In a recent meta-analysis of the efficacy and tolerability of 15 antipsychotic drugs it was found to produce the second least (after haloperidol) Weight gain, the least QT interval prolongation, the fourth most extrapyramidal side effects (after haloperidol, zotepine and chlorpromazine) Sixth least sedation (after paliperidone, sertindole, amisulpride, iloperidone and aripiprazole) Lurasidone is metabolized in the liver via the enzyme CYP3A4 This means that its plasma concentrations may be increased when combined with CYP3A4 inhibitors like ketoconazole or grapefruit juice, possibly leading to more side effects. |