As you have asked about the syllabus of the Graduate Pharmacist Aptitude test (GPAT), I am providing you with it, check below for the details

PHARMACEUTICS

Introduction to Physical pharmacy; Matter, Properties of Matter:

State of matter, change in the state of matter, latent heats and vapor
pressure, sublimation-critical point, Eutectic mixtures, gases, aerosols-
inhalers, relative humidity, liquid. complexes, liquid crystals, glassy state,
solids- crystalline, amorphous and polymorphism.

Micromeretics and Powder Rheology:

Particle size and distribution, average particle size, number and weight
distribution, particle number, methods for determining particle volume,
methods of determining particle size- optical microscopy, sieving,
sedimentation; measurements of particle shape, specific surface area;
methods for determining surface area; permeability, adsorption, derived
properties of powders, porosity, packing arrangement, densities, bulkiness &
flow properties.

Surface and Interfacial Phenomenon:

Liquid interface, surface and interfacial tensions, surface free energy,
measurement of surface and interfacial tensions, spreading coefficient,
adsorption at liquid interfaces, surface active agents, HLB classification,
solubilization, detergency, adsorption at solid interfaces, solid-gas and solid-
liquid interfaces, complex films, electrical properties of interface.

Viscosity and Rheology:

Newtonian systems, Law of flow, kinematic viscosity, effect of temperature;
non-Newtonian systems: pseudoplastic, dilatant, plastic; thixotropy,
thixotropy in formulation, negative thixotropy, determination of viscosity,
capillary, falling ball, rotational viscometers.

Dispersion Systems:

Colloidal dispersions: Definition, types, properties of colloids, protective
colloids, applications of colloids in pharmacy; Suspensions and Emulsions:
Interfacial properties of suspended particles, settling in suspensions, theory
of sedimentation, effect of Brownian motion, sedimentation of flocculated
particles, sedimentation parameters, wetting of particles, controlled
flocculation, flocculation in structured vehicles, rheological considerations;
Emulsions-types, theories, physical stability.

Complexation:

Classification of complexes, methods of preparation and analysis,
applications.

Kinetics and Drug Stability:

General considerations & concepts, half-life determination, Influence of
temperature, light, solvent, catalytic species and other factors, Accelerated
stability study, expiration dating.

Importance of microbiology in pharmacy; Structure of bacterial cell;
Classification of microbes and their taxonomy:

Actinomycetes, bacteria, rickettsiae, spirochetes and viruses;

Identification of Microbes:

Stains and types of staining techniques, electron microscopy; Nutrition,
cultivation, isolation of bacteria, actinomycetes, fungi, viruses, etc; Microbial
genetics and variation;

Control of microbes by physical and chemical methods:

Disinfection, factors influencing disinfectants, dynamics of disinfection,
disinfectants and antiseptics and their evaluation;

Sterilization:

different methods, validation of sterilization methods & equipments; Sterility
testing of all pharmaceutical products. Microbial assays of antibiotics,
vitamins & amino acids.

For more details, you can refer to the attached file

Attached Files

GPAT Syllabus.pdf (1.05 MB, 67 views)