#1
June 17th, 2016, 08:40 AM
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Recent Research In Nipper
Hii sir, I wants to get the names of the Recent Research projects of National Institute of Pharmaceutical Education and Research will you please provide me the names ?
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#2
June 17th, 2016, 08:41 AM
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Re: Recent Research In Nipper
NIPER is an Indian public Pharmacy research university, and a part of the seven schools, under India's Ministry of Chemicals and Fertilizers the Recent Research of the National Institute of Pharmaceutical Education are given below : Targeting signal transduction involved in microbial drug resistance Identification of new target protein(s) in insulin mediated signal transduction and in insulin resistance Enzyme drug interaction of medically important enzymes (Xanthine oxidase, HMG-CoA reductase etc.) Applied recombinant DNA technology for production of commercially important biochemicals Synthesis of Specific Cystein Proteinase and Tubulin inhibitors as potential Anti-parasitic agents. Synthesis of 8-aminoquinolines for broad-spectrum anti-malarial activity. Novel aza-aromatics for tuberculosis activity against M. tuberculosis. Alkaline-earth, lanthanide and transition metal based catalysts for acylation and nitration reactions under solvent free conditions. Chemoselective protection of phenols as alkyl ethers and acyl/aroyl esters; oximes as O-alkyl ethers and carboxylic acids as methyl esters exploiting the "Specific Solvation" and "Li+-Coordination" effects. Chemoselective deprotection of aryl-alkyl ethers and aryl/alkyl esters via in situ "Demand Based" generation of thiolate anions adopting the "Counter-attacking Agent" strategy. One-pot conversion of aldehydes to nitriles and benzothiazolines under conventional heating and microwave irradiation. One-pot conversion of carboxylic acids to benzothiazolines, benzoxazolines and benzimidazoles by microwave irradiation under solvent free conditions. 1,5-Diarylpyrazoles and 3,4-diaryloxazolones designed as potential COX-2 inhibitors. Tetrazole, pyrazole and biphenylic ethers designed as potential HMG-CoA reductase inhibitors. Azolidindiones, benzofurans and benzothiophenes have been designed as potential protein tyrosin phosphatase 1b inhibitors. Transition Metal Promoted Carbon-Carbon Bond Formation via Radical Intermediates: Synthesis of Heterocyclic Compounds. Synthesis of Ischemic Reperfusion Antagonist. Synthesis of New Chemical Entities as Anti-Leishmanials. Design and Synthesis of Potential Anti-Malarial Agents Having Blood- and Tissue-Schizontocidal Activity. Design, synthesis and biological evaluation of PDE4 Inhibitors as Potential Anti-asthma Agents. Design and synthesis of HDAC Inhibitors as Potential Anti-cancer Agents. Design, synthesis and biological evaluation of COX/LOX Dual Inhibitors as Potential Anti-inflammatory Agents. Design, synthesis and biological evaluation of XO Inhibitors as Potential Therapeutic Agents for Gout. Synthesis of diaryl ethers and diaryl sulfides as novel anti parasitic agents. Synthesis of small chalcone and stilbene libraries. Novel catalyst derived from transition, alkali and rare earth metals for electrophilic activation of epoxide for nucliophilic ring opening in stereoselective fashion. Synthesis of benzopyran, benzothiopyran and naphthopyran derivatives. Development of new multicomponent reactions for the preparation of imidazoles and their use in synthesis of purines. The synthesis of tetracyclic indenoindoles and their structural analogs as DNA intercalator and topoisomerase II inhibitor: Organoboron compounds as requisite radical precursors in intramolecular cyclization. Contact details : National Institute of Pharmaceutical Education and Research Sector 67, S.A.S. Nagar - 160062, Punjab (INDIA). Phone: +91(172)-2292000, 2214682-87 |
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