The Tamil Nadu Public Service Commission (TNPSC) is a department of the government of Tamil Nadu which is responsible for governing the recruitment of personnel into the state's public service

As per your demand here I am providing you syllabus of the Biochemistry of this Commission

Unit-1
Biomolecules Corbohydrates- Classification, Structure- Reactions-Oligosaccharaides - Poliysaccharaides-Structural Polysaccharides-Lipids-Classification-Simple-compound -Derived-biomembranes- Amino acidsClassification-reactions-peptides-Primary structures-Glutathione, Oxytocin -vasopressin-ProteinsClassification- Properties-Structure-Myoglobin & hemoglobin-Vitamins-Fat soluble-water solubleSources-structure-physiological functions

Unit-II
Techniques PH scale-Buffer solutions, buffer systems of blood,-Chromatography-principle, materials, methods and applications:- Paper chromatography, TLC, GLC, Adsorption, ion exchange, affinity chromatography and molicular sieve: principle of HPLC, Molecular weight determination by molecular sieve method. Electrophoresis-Ultracentrifuge-Separation of Cell organelles-Colorimetry-Spectrophotometry Fluorimetry-Flame photometer-Tracer-Techniques-Applications of radioisotopes in biological sciencesRadioisotopes in medical sciences.

Unit-III
Enzymes Enzymes- six main classes- Catalysis-Extraction, purification and characterization of enzyme kineticsEnzyme-inhibition-Ribozymes-Isozymes-Coenzymes-Multienzyme complex. Mechanism of enzyme action-immobilized enzymes

Unit-IV-
Intermediary Metabolism Bioenergetics-high energy compounds-free energy of hydrolysis-Glycolysis-TCA cycle-GluconeogneisisGlycogenesis-Pentose Phosphate pathway-Electron transport chain-Oxidative phosphorylationOxidation of fattyacids-beta oxidation-alpha oxidation-omega oxidation-Biosynthesis of-fatty acids and Cholesterol-Catabolism of amino acid-Oxidative deamination-transmination-decraboxylationMetabolism of Purines-Pyrimidines.

Unit-V-
Physiology Digestive system-Respiratory system-Blood-Body fluids-Nervous system-propagation of nerve impulse synaptic transmission-Neurotransmitters-Myosin and Actin and regulatory proteins-mechanism of contraction-Structure of nephron-renal regulation-Spermatogenesis-menstrual cycle-Pregnancy and lactation-steroid and glycoprotein-hormones-second messenger concept-CAMP.

Unit - VI –
Molecular Biology Bacterial transformation-transduction and conjugation-DNA replication in prokaryotes-eukaryotic replication-Prokaryotic transcription-Initiation, elongation and termination -Eukaryotic genenecleosomes-transcription factors-Processing of mRNA-Reverse transcription-Genetic code-tRNATranslation-Protein synthesis in prokaryotes.-Recombination-DNA repair mechanism-Excision repairgene regulation-gene mutation-reversion-Bacterial transposons.

Unit-VII –
Immunology Antibody mediated-Cell mediated response-lymphoid organs-neutrophils-macrophages-phagocytosisAntigens -antigenic determinants-haptans-Classes of Immunoglobulins-Antigen-antibody interactions in-vivo-complement component-Immuno electrophoresis-Cytokines.

Unit-VIII-
Clinical Biochemistry Diabetes mellitus-blood sugar GTT-Complications of diabetes-mellitus-Plasma lipidshyperlipoproteinemia-Type I, II, III, IV, and V-lipoproteinemia-atherosclerosis-Hypercholesterolemiatests of gastric function-Liver function tests-jaundice-Serum enzymes in liver disease-(SGPT) & SGOT)-Kidney function tests-creatinine and urea-Clearance.

Unit-IX –
Animal and Plant Cell Biotechnology Plant Tissue Culture-Micropropagation-Gene transfer in plants-Ti Plasmid vectors-Protoplast fusionTransgenic plants-Pest resistance-Mammalian cell culture- Cell-lines-Suspension culture; immobilizedcultivation-Gene transfer into mammalian cells-vectors; in vitro fertilization (IVF); embryo cloning.

Unit-X –
Plant Bio-chemistry Plant Cell- Cell wall-Organelles-Transport mechanisms-Absorption-Translocation of WaterTranspiration-Photosynthesis- Pigments-light obsorption- Photosystem-I-Photosystem-II-Calvin’s cycle (C3-Plants).- (C4 Plants)-Photorespiration-Nitrogen cycle-Nitrogen fixation.