#1
June 5th, 2015, 04:57 PM
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Osmania University Syllabus for M.Sc Organic Chemistry
I am the student of M.Sc Organic Chemistry in Osmania University and I want the syllabus so will you please provide me it in a pdf file? Tell me the link from which I can free download the syllabus and the previous year question papers of Osmania University? As you Asking for the Syllabus of the Subject Conformational Analysis, Asymmetric Synthesis and Biomolecules of the MSc Organic Chemistry III Semester of the Osmania University the Syllabus is As Follow Conformational Analysis, Asymmetric Synthesis and Biomolecules - Conformational analysis (Cyclic systems) Study of conformations of cyclohexane, mono, di and polysubstituted cyclohexanes, cyclohexene, cyclohexanone (2-alkyl and 3 -alkyl ketone effect), 2-halocyclohexanones, cyclopentane, cyclobutane, cycloheptane and cyclooctane, Stereo chemistry of bicyclo[3,3,0]octanes, hydrindanes, decalins and perhydroanthracenes. Conformational structures of piperidine, N-Methylpiperidine, tropane, tropine, pseudotropine, decahydroquinoline and quinolizidine. Conformaijonal effects on the stability and reactivity of diastereomers in cyclic molecules - steric and stereo electronic factors - examples Factors governing the reactivity of axial and equatorial substituents in cyclohexanes. Stereochemistry of addition to the carbonyl group of a rigid cyclohexanone ring. OC l0- Principles of asymmetric synthesis Introduction and terminology: Topicity in moleculesHomotopic, stereoheterotopic (enantiotopic and diastereotopic) groups and faces- symmetry, substitution and addition criteria.Prochirality nomenclature: Pro-R, Pro-S, Re and Si. Stereoselective reactions: Substrate stereoselectivity, product stereoselectivity, enantioselectivity and diastereoselectivity. Conditions forstereoselectivity: Symmetry and transition statecriteria, kinetic and thermodynamic control. Methods for inducing enantio and diastereoselectivity. Analytical methods: % Enantiomeric excess, enantiomeric ratio, optical purity, % diastereomeric excess and diastereomeric ratio. Techniques for determination of enantiomeric excess, specific rotation, Chiral NMR; Chiralderivatizing agents, Chiral solvent, Chiral shift reagents and Chiral HPLC. OC 11- Methodologies in asymmetric synthesis Strategies in Asymmetric Synthesis: l. Chiral substrate controlled, 2. Chiral auxiliary controlled, 3. Chiral reagent controlled and 4. Chiral catalystcontrolled. 1. Chiral Substrate controlled asymmetric synthesis: Nucleophilic additions to chiral carbonyl compounds. 1, 2- asymmetric induction, Cram’s rule and Felkin-Anh model. 2. Chiral auxiliary controlled asymmetric synthesis: α-Alkylation of chiral enolates, azaenolates, imines and hydrazones. 1, 4-Asymmetricinduction and Prelog’s rule. Use of chiral auxiliaries in Diels-Alder reaction. 3. Chiral reagent controlled asymmetric synthesis:Asymmetric reductions using BINAL-H. Asymmetric hydroboration using IPC2BH and IPCBH2. 4. Chiral catalyst controlled asymmetric synthesis: Sharpless and Jacobsen asymmetric epoxidations. Sharpless asymmetric dihydroxylation. Asymmetric hydrogenations using chiral Wilkinson biphosphine and Noyori catalys. Enzyme mediated enantioselective synthesis 5. Asymmetric aldol reaction: Diastereoselective aldol reaction (chiral enolate & achiral aldehydes and achiral enolate & chiral aldehydes) its explanation by Zimmerman-Traxel model. OC-12 Biomolecules 1. Enzymes: Definition. Classification based on mode of action. Mechanism of enzyme catalysis. Lock and Key model and Induced- Fit model. Enantiomer discrimination by Three- point Contact model. Factors affecting enzyme catalysis.Enzyme inhibition- reversible and irreversible inhibition. Enzymes in organic synthesis. Immobilised enzymes. 2. Nucleic acids:Primary, secondary and tertiary structure of DNA. Types of mRNA,tRNA and rRNA. Replication, transcription and translation. Genetic code. Protein biosynthesis. Chemical Synthesis of nucleosides and nucleotides. 3. Lipids:Lipid structure- acylglycerols, phosphoglyceridesand sphingolipids. Biosynthesis of Lipids and chemical Synthesis of lipids. For any Query you may Contact to the Osmania University the Contact details Are given below Contact details : Osmania University Address: Osmania University Main Rd, Osmania University, Amberpet, Hyderabad, Telangana 500007 Phone: 040 2768 2444 Last edited by Neelurk; February 10th, 2020 at 01:41 PM. |
#2
March 9th, 2017, 08:21 AM
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Re: Osmania University Syllabus for M.Sc Organic Chemistry
Hii sir, I Wants to get the Syllabus of the Subject Conformational Analysis, Asymmetric Synthesis and Biomolecules of the MSc Organic Chemistry III Semester of the Osmania University ?
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