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August 14th, 2014, 11:20 AM
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GPAT exam previous year paper
Here I am looking for the GPAT exam previous year paper, will you please provide me the same????????? This is the GPAT exam previous year paper: GPAT exam previous year paper 1) The following gibberalin derivative is known as gibberalic acid………… a) GA1 b) GA2 c) GA3 d) GA4 2) The following is the precursor for the synthesis of Dhurrin in sikkimic acid pathway………….. a) Phenylalanine b) Tyrosine c) Linamarin d) Lotuustralin 3) Multicellular branched covering peltate trichomes are characteristic for………….. a) Hammelis b) Humulus c) Verbascum Thapsus d) All of the above 4) Ranunculaceous stomata is the characteristic for …….. a) Buchu b) Digitalis c) Lobelia d) All of the above 5) Moisture content limit for digitalis should not be more than…… a) 10 b) 05 c) 08 d) 15 6) The fluorescence exhibited by rhubarb under UV light is……………. a) Purple blue b) Whitish blue c) Viloet d) Mauve 7) For the measurement of hypoglycemic activity, the following herbal extract is used………….. a) karela b) Jambul c) Fenugreek d) All of the above 8) The total aerobic microbial load per gram of material ready for internal use is…………. a) 105 b) 102 c) 10 d) 103 9) Outgrowth arista( awn) is found in following drug…… a) Cardamom b) castor c) Nutmeg d) Stropanthus 10) The cathartic principle in momordica charantia is……. a) Charantin b) Momordicin c) saponin d) Glucoside 11) From the following which one is immunomodulator drug,,,,,,,,,,,,, a) Brahmi b) Jatamansi c) Ginseng d) All of the above 12) Rhytidoma is the characteristic for…….. a) Gokhru b) Rattle snake root c) Quillaia d)Brahmi 13) The bitter taste of gentiana lutea is due to……. a) Gentisin b) Gentianine c) Amarogentin d) gentiopicrin 14) The following is the example of non-drying oil……….. a) Oilve oil b) Peanut oil c) Almond oil d) All of the above 15) Badouin’s test is given by……………. a) Sesame oil b)Oilve oil c) Peanut oil d) Almond oil 16) Carr price reaction is positive in case of…………… a) Vit.A b) Vit.B c) Vit.D d) Vit.B7 17) The following variety of cardamom does not show rugae among all the varieties………….. a) Allepy cardamom b) Mysore cardamom c) Korarima cardamom d) Malabar cardamom 18) The following microscopical characters are true for fennel except… a) Anomocytic stomata b) Lignified and reticulate parenchyma c) Rossete crystals of ca-oxalate d) Trichomes and starch grains are absent 19) The outgrowth of nutmeg contains amylodextrin which gives following colour with iodine………… a) red colour b) Blue colour c) Pink colour d) white colour 20) The following microscopical characters are false in case of Clove except one….and it is…. a) Clove contains diacytic stomata b) Clove contains starch c) Scizogenous oil glands d) It contains anomocytic stomata 21) Ca-oxalate crystals and starch grains are absent in….. p) Fennel q) Stropanthus r) Nux-vomica s) Physostigma a) p,q b) p,r c) q,s d) r,s 22) The following variety is the commercial source of reserpine………….. a) R.tetraphylla b) R.Vomitoria c) R.serpentina d) R.densiflora 23) Vitali-morin reaction is positive in case of……… a) Tropane alkaloids b) Quinoline c) Isoquinoline d) Purine alkaloids 24) Sunken trichomes and sunken stomata are present respectively in following drug…… p) Ephedra q) Colchicum r) Lobelia s) Gloriosa a) p,r b) r,p c) q,r d) p,q 25) The IUPAC name for Prazepam is…… a) 7-chloro-1-methyl-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one b) 8-chloro-1-( Cyclobutylmethyl)-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one c) 7-chloro-1-( Cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one d) 8-chloro-1-( Cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one 26) Buspirone contain following ring system………. a) Spiran b) Piperazine c) Pyrimidine d) All of the above 27) 4-[3-[2-( trisfluoromethyl) phenazin-10-yl]propyl]-1-piperazineethanol tends for…………….. a) Perphenazine b) Fluphenazine c) Acetophenazine d) Trifluoperazine 28) 6-[ 2,3-dichloro phenyl)]-3,5-diamino triazine tends for following category of drug…………….. a) Anti-depressant b) Anti-psychotic c) Anxiolytic drug d) Anti-epileptic drug 29) The following is CNS stimulant drug….. a) Mazindol b) Phendimetrazine c) Pemoline d) All of the above 30) The tricyclic anti-depressant drug trazodone contain following ring system………… a) Piperazine b) Triazole c) Pyridine d) All of the above 31) The following is true for dobutamine except…. a) B1- receptor agonist b) it is used in cardiogenic shock c) (-) enantiomer is potent α1 agonist d) (-) enantiomer is potent α2 agonist 32) The following drugs are used in benign prostatic hypertrophy ( BPH) ……………. p) Tamsulosin q) Clonidine r) Mifepristone s) Finasteride a) p,r b) p,q c) p,s d) q,r 33) The mechanism of corynanthine is…………… a) Selective α2 receptor antagonist b) Selective α1 receptor antagonist c) non-selective α receptor antagonist d) Selective β1-receptor agonist 34) Occulomucocutaneous syndrome is the side effect of following drug…… a) Metoprolol b) Practolol c) Albuterol d) Atenolol 35) The following drug is safe in hypertension in pragnency …………… p) Methyl dopa q) Labeatalol r) Carvediol s) Ritodrine a) p,s b) q,s c) p,q d) q,r 36) The following is the quinazoline ring containing drug……………….. a) Prazosin b) Methaqualone c) Metolazone d) All of the above 37) The IUPAC name for amiloride is……………. a) 3,4-diamino-N-( aminoiminomethyl)-6-chloropyrazine carboxamide b) 3,4-diamino-N-( aminoiminomethyl)-6-chloropiperazine carboxamide c) 3,5-diamino-N-( aminoiminomethyl)-6-chloropyrazine carboxamide d) 3,5-diamino-N-( aminoiminomethyl)-6-chloropyridine carboxamide 38) 1-methyl-2-( 2,6-xylyloxy)-ethylamine is the IUPAC name for………………. a) Lidocaine b) Mexiletine c) Encainide d) Flecainide 39) The following drug is only acting as arterial vasodilator…………. a) Hydralazine b) Na-nitroprusside c) Diazoxide d) Minoxidil 40) Among all the sulfonyl ureas, the following drug is having longer duration of action….. a) Tolbutamide b) Chlorpropamide c) Acetohexamide d) Tolazamide 41) To filter the slurries containing the solids not more than 5 %, the following filter is used……….. a) Filterpress b) Filterleaf c) Meta fliter d) Membrane filter 42) If carr’s index is 23-35 then flow is …………… a) Excellent b) Fair to passable c) Poor d) Extremely poor 43) If the PKa of Phenobarbitone is 7.4.what fraction of drug would be ionized at pH 8.4?………….. a) 0.01 b) 0.50 c) 0.90 d) 1.00 44) The following is the example of cationic surfactant…………………… a) Benzalkonium chloride b) Polysorbate 80 c) SLS d) Sorbitan monooleate 45) The type of particle diameter that is obtained by microscopic method of evaluation is……………….. a) Projected b) Stokes’ c) Volume d) Volume-surface 46) HEPA filters are widely used in ……………….. a) Autoclaves b) Laminar air flow hoods c) Gas sterilizers d) Oxygen masks 47) Inversion sucrose in syrup due to heat is known as……………. a) Isomerization b) Epimerization c) Tautomeriation d) caramelization 48) carnauba wax is used in the following step of sugar coating of tablet: a) Seal coating b) Polishing c) Sub-coating d) Syrup coating 49) One of the following diluent may discolour in the presence of amine containing drugs: a) Avicel b) DCP c) Lactose d) Talc 50) Cam tracks are used in tablet formulation for……………… a) Feeding the granules b) Fixing the shape c) Compressing the granules d) Guiding the movement of punches 51) Non-ionic surfactant vesicles relates to………. a) Liposomes b) Niosomes c) Nanoparticles d) a and b both 52) Water insoluble coating materials used for microencapsulation include…………… a) Ethyl cellulose b) Polyethylene c) Polyamide d) All of the above 53) Schedule U1 tends for………………………. a) Manufacturing and analytical records of drugs b) Manufacturing and analytical records of cosmetics c) Standards for patent or proprietary medicines d) List of drugs marketed under generic name only 54) The test which is useful for the identification of M. tuberculosis……………. a) Haemolysis b) Fermentation with sugar c) Gram-staining d) Zeihl-nelson staining 55) The following type of antigen associated with capsules………….. a) H-antigens b) 0-antigens c) V-antigens d) K-antigens 56) Colchicine when treated with 70 % H2SO4 or HCL gives following colour………………… a) Red colour b) Blue colour c) Green colour d) yellow colour 57) Quinine gives following positive test…………… a) Herpathite test b) Thaleoquin test c) Rosequin test d) All of the above 58) Schilber reagent is used for the detection of…………….. a) Glycosides b) Volatile oils c) Alkaloids d) Tannins 59) Noller test is used for the detection of……………….. a) ) Glycosides b) Volatile oils c) Alkaloids d) Tannins 60) Vit.requirement for microorganism Sytreptococcus pyogenes is…… a) Tryptophan b) Glutathione c) Riboflavin d) Vit.B12 61) The test organism used for validation of filtration sterilization is…….. a) Serratia marscenes b) Pseudomonas dimunata c) Vibrio percolans d) All of the above 62) The biological source for Cycloserine is………… a) S.Orchidaceus b) S.garyphyllus c) S.lavandulus d) All of the above 63) Which of the following drug used in digitalis induced arrhythmias?…………. a) Verapamil b) Phenytoin c) Flecainide d) Procainamide 64) Aspartame is chemically……………. a) Methyl ester of aspartic acid and phenylalanine b) Methyl ester of phenylalanine and aspartic acid c) Ethyl ester of phenyl alanine and aspartic acid d) Ethyl ester of aspartic acid and phenyl alanine 65) Which of the following is used as a bulk property detector in HPLC? a) UV-visible detector b) Diode array detector c) Refractive index detector d) Fluorescence detector 66) Which of the following drug is biosynthesized from Lysine? a) Pilocarpus b) Asthma weed c) Aconite d) Holarhhena 67) Sugar coated tablet having disintegration time is…………… a) 15 min b) 60 min c) 30 min d) 45 min 68) Drugs used in the treatment of Insulinoma is…………… a) Chlorambucil b) Tolbutamide c) Streptozotocin d) Melphalan 69) Which of the following used as stabilizer in the parenteral products………..? a) Na sulfate b) Na caprylate c) Na desoxycholate d) Na CMC 70) Most commonly used radiation source in atomic absorption spectroscopy is……………. a) Tungsten lamp b) Xenon discharge lamp c) Hollow cathode lamp d) Mercury vapour lamp 71) Anorgasmia side effect produced by………….. a) Selective serotonin reuptake inhibitor b) Tricyclic antidepressant c) Monoamine oxidase inhibitors d) All of the above 72) Which of the following drug is contraindicated in type IIa hyperlipoproteinamia……….? a) Probucol b) Colestipol c) Acipimox d) Fish oil 73) Mediastinal fibrosis side effects produced by…………….. a) Propranolol b) Sumatriptan c) Methysergide d) Cyproheptadine 74) Number of peaks given by 1H NMR spectrum of P-xylene is………….. a) 4 b) 1 c) 2 d) 3 75) USP dissolution apparatus 4 used for …………… a) Capsule b) Tablet c) Low solubility of drugs d) Emulsion 76) The heterocyclic ring present in dipyridamole is……….. a) Pyridine b) Piperidine c) Pyarazine d) Piperazine 77) Which form no is used for import of biological drugs( C/C1)………… a) 9 b) 12-A c) 11-A d) 24-A 78) Paper chromatography is based on……………. a) Adsorption b) Exclusion c) Affinity d) Partition 79) α-[ 2-( diisopropylamino) ethyl]-α-phenyl-2-pyridine acetamide is…………….. a) Amiodarone b) Mexiletine c) Disopyramide d) Procainamide 80) Which of the following is non-competitive inhibitor of citric acid cycle enzyme called α-ketoglutarate dehydrogenase? a) Fluoroacetate b) Arsenite c) Melonate d) Lithium 81) Imipenam is………… p) Obtained from chromobacterium violaceum q) It is given with cilastatin r) It is monocyclic s) Obtained from streptomyces cattelya a) p,q b) q,s c) p,r d) r,s 82) Riedal-walker test …… p) Measure the effectiveness of antibiotics q) test organism E.coli r) Test organism salmonella typhi s) Measure effectiveness of anticeptics a) p,q b) q,s c) p,r d) r,s 83) Which of the following problems associated with glass containers? p) Weathering q) Corrosion problem r) Flaking s) Breathing a) p,q b) p,r c) p,s d) r,s 84) Which transitions are given by benzoic acid under UV spectra……………… p) n π* q) π π* r) n δ* s) δ δ* a) q,r b) r,s c) p,r d) p,q 85) Which of the following bio-chemical tests given by phenolic group containing amino acids……..? p) Nin-hydrine reaction q) Nitroprusside reaction r) Millon’s reaction s) Folin- coicalteau’s test a) p,s b) q,r c) r,s d) p,r 86) In aerosol container, gasket is made up of………………… p) Buna-N q) Neoprine rubber r) Nylon s) Delrin a) p,q b) q,r c) p,s d) p,r Common data questions: 87) Sex pheromones used as……….. a) Sex hormones b) Fertilizers c) Plant growth regulators d) Pest control agent 88) Example of sex pheromones is……….. a) Nitrogen b) testosterone c) 7,8-epoxy 2- methylloctadecane d) Abscisic acid 89) Starting material for the synthesis of cinchocaine is……………… a) o- toluidine b) Picolinic acid c) Isatin d γ- picoline 90) The IUPAC name for cinchocaine is…………. a) 2-butoxy-N-[ 2-( dimethylamino)methyl]-quinoline-4-carboxamide b) 2-butoxy-N-[ 2-( diethylamino)ethyl]-quinoline-4-carboxamide c) 2-ethoxy-N-[ 2-( dimethylamino)ethyl]-quinoline-4-carboxamide d) 2-ethoxy-N-[ 2-( diethylamino)methyl]-quinoline-4-carboxamide In a formulation laboratory , tablet is to be formulated,the core tablet has bad taste and required protection from moisture.The Tablet should also deliver the drug for local action in intestine: 91) Suggest suitable method……… a) Sugar coating b) Film coating c) Enteric coating d) Sub-coating 92) Choose the correct coating material…………. a) Sugar b) Acacia c) EC d) Acrylates Linked questions: Triamterine is diuretic drug.it is potassium sparing diuretic………. 93) It contains which is containing heterocyclic ring? a) Quinoline b) Quinazoline c) Pteridine d) Pyrimidine 94) It’s mechanism of action is………….. a) Aldosterine antagonist b) Block luminal Na+ channel c) Block Na+/K+/2Cl- tranporter d) Block Na+/Cl- transport 95) Pyrilamine is antihistaminic drug………….. Pyrilamine is chemically……………… a) Amino alkyl ether b) Imidazole analogue c) Ethylene diamines d) Propylamines 96) Pyrilamine maleate is assayed as per IP by titrating with a) 0.1 M NaOH b) 0.1 M Perchloric acid c) 0.1 M HCL d) 0.1 M silver nitrate As per the woodward-fieser rule,the absorption maxima of the compound shown is calculated from the base value and the ring Residue values…………. 97) Base value is……. a) 215 nm b) 253 nm c) 240 nm d) 217 nm 98) Absorption maxima is………… a) 220 nm b) 230 nm c) 258 nm d) 268 nm An organic compound ” X” has an absorption maxima at 217 nm.It’s Emax is 16,000.The absorbance is 0.64 when the cell length is 1 cm.. The decomposition of drug in aqueous acid solution was found to follow first order reaction.The initial concentration was found To be 0.056 M.The initial Concentration was found to be 0.056 M.The concentration after a period of 12 hrs was 4.10×102- Moles/liter.The reaction rate constant is 0.02599 hr1- 99) What is the quantity of the drug remaining undecomposed after 8 hrs……..? a) 0.455 moles/litre b) 0.25 moles/ litre c)0.0455 moles/litre d) 0.10 moles/litre 100) What is the amount of drug deteriorated during the period of 24 hrs? a) 0.026 moles/litre b) 0.0026 moles/litre c) 0.03 moles/litre d) 0.053 moles/litre Answersheet 1 c 21 b 41 b 61 d 81 b 2 b 22 b 42 c 62 d 82 d 3 b 23 a 43 c 63 b 83 b 4 d 24 b 44 a 64 a 84 b 5 b 25 c 45 a 65 c 85 b 6 c 26 d 46 b 66 b 86 a 7 d 27 b 47 d 67 b 87 d 8 a 28 d 48 b 68 c 88 c 9 d 29 d 49 c 69 b 89 c 10 b 30 d 50 d 70 c 90 c 11 c 31 d 51 b 71 a 91 c 12 c 32 c 52 d 72 d 92 d 13 c 33 b 53 b 73 c 93 c 14 d 34 b 54 d 74 c 94 a 15 a 35 c 55 d 75 c 95 c 16 a 36 d 56 d 76 b 96 b 17 c 37 c 57 d 77 a 97 a 18 d 38 b 58 c 78 d 98 b 19 a 39 a 59 b 79 c 99 c 20 d 40 b 60 c 80 b 100 a Last edited by Neelurk; April 28th, 2020 at 10:52 AM. |
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