As you want to download syllabus of Graduate Pharmacy Aptitude Test (GPAT), so here I am providing syllabus:

1. Graduate Pharmacy Aptitude Test (GPAT) Syllabus

PHYSICAL CHEMISTRY
1. Composition & physical states of matter
Intermolecular forces & their impact on state of the matter. Various physical propertiesof matter, dipole moment, dielectric constant, Van Der waal's equation & criticalphenomenon, liquefaction of gases, aerosols.

2. Colligative Properties
The liquid state, vapor pressure, ideal & real solutions. Raoult's law, elevation of boilingpoint, depression of freezing point, osmotic pressure, determination of molecularweight based on colligative properties.

3. Thermodynamics
First, second & third law of thermodynamics. Thermochemical laws, isothermic &adiabetic processes, reversible processes, work of expansion, heat content, enthalpy,heat capacity. Gibb's & Helmoltz equation & chemical potential.

4. Chemical Equillibria.

5. Phase rule
One, two, & three component systems along with their applications.Solid- solid, solid -liquid, & liquid-liquid systems.Distillation of binary systems, azeotropic mixtures,steam, vacuum, & fractional distillation.

6. Refractive index
Refractive index, specific refractivity, molar refractivity, refractometers.

7. Solutions
Solubility, factors affecting solubility, solubility curves. Types of solutions, effect of cosolvancy,pH & other factors on solubility. Solubility of gases in liquids, liquids inliquids, & solids in liquids, critical solution temperature, law of partitioning & itsapplications.Solute solvent interactions.Expression of concentration of pharmaceuticalsolutions & calculations.Molarity, molality, mole fraction & percentage expressions.

8. Electrochemistry
Properties of electrolyte solutions, electrolysis. Faraday's law of electrolysis, electrontransport, electrical cell, single electrode potential, concentration cells, half-cells & halfcell potential, types of half cells, sign convention, Nerst equation, salt bridge,electromotive series, standard potential, SHE. Measuring the relative voltage of halfcells, Calculation of standard potential.Reference & indicator electrodes.Standardoxidation-reduction potential.

9. Ionic equilibrium
Theory of conductivity, equivalent conductance, mobility of ions, specific conductance.

10.Kinetics
Order of reactions, derivation & internal form of rate laws, molarities of reaction,derivation of rate constants.

PHYSICAL PHARMACY
1. Matter, properties of matter
States of matter, change in the state of matter, latent heat and vapor pressure,sublimation-critical point, eutectic mixtures, gases, aerosols- inhalers, relativehumidity, liquid complexes, liquid crystals, glasses state, solid crystalline andamorphous polymorphism.

2. Micromeritics and powder rheology
Particle size and distribution, average particle size number and weight distribution,particle number, method of determining particle size and volume, optical microscopy,sieving, sedimentation, determining surface areas, permeability, adsorption, derivedproperties of powders, porosity, packing arrangement densities, bulkiness and flowproperties.

3. Surface and interfacial phenomenon
Liquid interface, surface and interfacial tensions, surface free energy, measurement ofsurface and interfacial tension, spreading coefficient, adsorption and liquid interfaces,surface active agents, HLB classification, solubilization, detergency, absorption at solidinterfaces, solid gas and solid liquid interfaces, complex films, electrical properties ofinterfaces.

4. Viscosity and rheology
Newtonian systems, law of flow, kinematics viscosity, effect of temperature, nonNewtonian systems, pseudoplastics, dilatant, plastic, thixotropy in formulations,determination of viscosity and thixotropy bycapillary, falling ball, rotationalviscometer, application of theology in pharmacy

5. Dispersion systems
a. Colloidal dispersions: Definition, types, properties of colloids, protectivecolloids, application of colloids in pharmacy.

b. Suspensions and emulsions: Interfacial properties of suspended particlessettling in suspension, theory of sedimentation, effect of Brownian movement,sedimentation of flocculated particles, sedimentation parameters, wetting ofparticles, significance of electrical properties in dispersions, controlledflocculation, flocculation in structured vehicles, rheological considerations,emulsions: types, theories, physical stability

Graduate Pharmacy Aptitude Test (GPAT) Syllabus

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