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Q.1 Under alkaline conditions, DNA is more stable than RNA because
(A) RNA forms secondary structures
(B) RNA is a single stranded molecule
(C) RNA has uracil in place of thymidine
(D) RNA is susceptible to hydrolysis
Q.2 Which one of the following modifications is common toboth protein and DNA?
(A) SUMOylation (B) Nitrosylation (C) Methylation (D) Ubiquitination

Q.3 Protein A, which has strong affinity to Fc region of immunoglobulin, is extracted from
(A) Saccharomyces cerevisiae (B) Staphylococcus aureus
(C) Streptococcus pyogenes (D) Streptococcus sanguis

Q.4 The first humanized monoclonal antibody approved for the treatment of breast canceris
(A) Rituximab (B) Cetuximab (C) Bevacizumab (D) Herceptin

Q.5 Which one of the following aminoacids in proteins does NOT undergo phosphorylation?
(A) Ser (B) Thr (C) Pro (D) Tyr

Q6. The role of an aduvant isto
(A) prolong the persistence of antigen
(B) cross link the antigen
(C) increase the size of antigen
(D) avoid inflammation

Q7. Endogenous antigens are presented on to the cell surface along with
(A) MHC-II (B) MHC-I (C) Fc;receptor (D) complement receptor

Q.8 Human genome sequencing project involved the construction of genomic library in
(A) Bacterial artificial chromosome (B) pBR322
(C) Bacteriophage (D) pcDNA3.1

Q.9 The nucleotide analogue used in DNA sequencing by chain termination method is
(A) 1',3'-dideoxy nucleoside triphosphate
(B) 2',3'-dideoxy nucleoside triphosphate
(C) 2',4'-dideoxy nucleoside triphosphate
(D) 2',5'-dideoxy nucleoside triphosphate
Q.10 In nature, the horizontal gene transfer across bacteria is mediated by
(A) Gene cloning followed by transformation
(B) Conjugation and transformation
(C) Conjugation only
(D) Transformation only

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