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June 27th, 2016, 01:05 PM
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NIPER JEE Study Material
Hii sir, I wants to get the syllabus of the NIPER JEE Entrance Exam will you please provide me the syllabus of the NIPER JEE Entrance Exam ? National Institute of Pharmaceutical Education and Research (NIPER) has been created as a center of excellence for higher training, research and development in pharmaceutical sciences and technology and its first institute of this kind in the country. The syllabus of the NIPHER JEE Examination is as follow : Natural Products: In natural products more stress should be given on phytochemistry part rather than biological aspects. Methods of extraction, isolation and characterization of natural products. Various separation techniques used for isolation of natural products. Biosynthetic pathways. Primary metabolites, their examples. Secondary metabolites, various classes of secondary metabolites (e.g. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, anthocyanidines etc.). Here most imp. Part is chemistry of these classes. Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc. Dietary antioxidants, Marine natural products, Plant growth regulators. Spectroscopy: Basic concepts of UV, NMR, IR and Mass spectroscopy. Give more stress on IR and NMR. Stereochemistry: Basic concepts. Fischer, sawhorse and newmon projection formulaes. Biological sources of important classes of natural products. (Selected ones only) Standardization of natural products. What is difference between natural products and pharmacognosy? Pharmacology and toxicology: Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects. Bioavailability, bioequivalence, various factors of ADME. (From Bramhankar) Drug metabolism: various pathways and other details. Drug interactions, agonist, antagonist, partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc. Pharmacological screening: general principles, various screening models, screening methodologies (in vitro and in vivo tests). Mechanism of drug action, drug-receptor interaction. Various adrenergic, cholinergic and other receptors Detailed study of CNS pharmacology Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure. Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion. Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases. Bioassay methods, various requirements. Brief knowledge of the statistical tests. NIPHER JEE Examination Syllabus Practice of Pharmacy: 1.Adverse Drug Reactions . 2.Rational drug use as well as some typical case studies in diabetes and hypertension and some case study regarding Anti- infective therapy, Diabetes, Heart diseases are important. 3.Therapeutic drug monitoring 4.Hospital pharmacy 5.Clinical pharmacy References : Roger Walker for some Adverse Drug Reactions and some tables Remington’s Pharmaceutical Sciences. Pharmacoinformatics: 1.Terminologies related with new emerg ing informatics e.g. proteomics, genomics, QSAR (2D, 3D, regression, correlation). 2.Specially , which software is used for what purpose? References: QSAR chapter from Bothra Foye, Williams and Lemke, Medicinal chemistry, 5th/6th edition, chapter 1 -6. (Computational drug design and molecular modeling). Biotechnology: 1.General knowledge and understanding of cycles, carbohydrates, mucopolysacch arides, proteins, lipids, amin o acid their metabolism 2.Enzymes - types of enzymes, allosteric inhibition and enzy me kinetics etc. 3.General understanding of V itamins 4.Staining. 5.Understanding of HIV, Influenza, Cancer (Role of DNA and Telomerase) . 6.Genetic Engg: Gene expression, mutation, replication, transcription, translation, recombination, bacteriophages 7.Cloning: methods, isolation of nucleic acids, enzymes in cloning (restriction endonucleases, DNA ligase, DNA gyrase, polymerases et c), and functions of these enzymes. Microassays - PCR, Blotting. Pallindromes. 8.Fermentation: fermenters, fermentation process, i ts regulation, conditions, bioprocessors, various enzymes in fermentation technology. Fermentation of Antibiotics (fermentation of penicillin, cephalosporins, streptomycin - organisms used ), vitamins (B12), amino acids, organic acid production- hydroxy acids such as lactic acid etc. Chemical engineering aspects related to fermentation 9.Monoclonal antibodies, insulin, interferons, enkephalins, angiotensin analogues and other peptides. 10.Gene therapy: methods and applications. 11.Vaccines and their storage. 12.Use of microorganisms in pharmaceutical industries. 13.Haematic diseases - anaemia, thalassemia, porpyhyrins. 14.DNA purification, mutation. 15.Electrophoresis. 16.Tests of biochemistry References: Vyas and Dixit IP Appendices U. Satyanaray ana See some intr o chapters from Tortora and Industrial Microbiology also. Kokare is best. Pharmaceutical analysis: 1.Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability. 2.Var ious analytical techniques 3.Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests. 4.Spectroscopic methods; UV, NMR, IR, MS, FT -IR, FT -NMR, ATR (Attenuated Total Reflectance), FT -Ram an-basics and applications For the detail Syllabus Consider the below attachement that is Free to Download; Last edited by Neelurk; May 30th, 2020 at 11:35 AM. |
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