|
#1
June 19th, 2014, 01:24 PM
| |||
| |||
| RRB Pharmacist Post Exam Model Paper
Can you give me question paper for railway recruitment board Pharmacist Post Examination ? Here I am giving you question paper for railway recruitment board Pharmacist Post Examination in file attached with it so you can get it easily. . Ethambutol molecule has • two chiral centers and 3 stereoisomers • two chiral centers and 4 stereoisomers • two chiral centers and 2 stereoisomers • one chiral centers and 2 stereoisomers A compound will be sensitive towards IR radiation only when one of the following properites undergo transition on radiation Polarizability • Dielectric constant • Dipole moment • Refractivity X-ray crystallographic analysis of an optically active compound determines its Optical rotatory despersive power • Absolute configuration • Relative configuration • Optical purity Which one ofthe following statements is WRONG A singlet or triplet state may result when one of the electrons from the HOMO is excited to higher energy levels • In an excited singlet state, the spin of the electron in the higher energy orbital is paired with the electron in the ground state orbital • Triplet excited state is more stable than the singlet excited state • When the electron from the singlet excited state returns to ground state, the molecule always shows fluorescence phenomenon Aminotransferases usually require the following for their activity : Niacinamide • Vitamin B12 • Pyridoxal Phosphate • Thiamine Purity of water can be assessed by determining one of its following properties instrumentally : • pH • Refractivity • Viscosity • Conductivity Which one of the following statement is WRONG • Carbon NMR is less sensitive than Proton NMR • C-12 nucleus is not magnetically active • Both C13 and H1 have same spin quantum numbers • The gyromagnetic ratio of H1 is lesser than that of C13 In the TCA cycle, at which of the following ezyme-catalyzed steps, incorporation of elements of water into an intermediate of the cycle takes place • Citrate synthase • Aconitase • Malate dehydrogenase • Succinyl Co-A synthase Humectants added in cosmetic preparations generally act by • Hydrogen bond formation • covalent bond formation • complex formation • the action of London forces In the mixing of thymol and menthol the following type of incompatibility occurs • Chemical incompatibility • Therapeutic incompatibility • Physical incompatibility • Tilerance incompatibility Bloom strength is used to check the quality • Lactose • Ampoules • Hardness of tablets • Gelatin The characteristic of non-linear Pharmacokinetics includes • Area under the curve is propotional to the dose • Elimination half-life remains constant • Area under the curve is not propotional to the dose • Amount of drug excreted through remains constant In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is • Schedule M • Schedule C • Schedule Y • Schedule H Thioglycolic acid-like compounds have applications in the following type of cosmetic formulations • Depilatory preparations • Epilatory preparations • Vanishing creams • Skin tan preparations Which one of the following is a flocculating agent for negatively charged drug? • Aluminium chloride • Bentonite • Tragacanth • Sodium biphosphate The healing agent used in hand creams is • soft paraffin • urea • bees wax • steryl alcohol Measurement of inulin reanal clearance is a measure for • Effective renal blood flow • Ranal drug excretion rate • Active renal secretion • Glomerular filtration rate Highly branched three dimenssional macromolecules with controlled structure with all bonds originating from a central core are known as • Cyclodextrins • dextrans • dendrimers • liposomes Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products • sodium chloride • mannitol • starch • HPMC The applicability of Noyes-Whitney equation is to describe • First order kinetics • Zero order kinetics • Mixed order kinetics • Dissolution rate The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been attributed to its catabolism to dopamine. Carbidopa, can markedly increase the proportion of levodopa that crosses the blood-brain barrier by: increasing penetration of levodopa through BBB by complexation with it decreasing peripheral metabolism of levodopa decreasing metabolism of levodopa in the CNS decreasing clearance of levodopa from the CNS Drugs in suspensions and semi-solid formulations always degrade by first order kinetics zero order kinetics second order kinetics non-linear kinetics Tropane alkaloids are NOT present in Datura stramonium Erythroxylum coca Duboisia myoporoides Lobelia inflata In nucleophilic aliphatic substitution reactions the ability of the following leaving groups  P) Fluoride (Q) Iodide (R) Chloride (S) Bromide follows the order P > Q > R > S R > S > Q > P Q > S > R > P P > R > S > Q In sequence rules, the priority of the following atoms attached to chiral carbon is to be decided for designating its absolute configuration: (P) Oxygen (Q) Carbon (R) Nitrogen (S) Hydrogen Priority of the atoms is to be decided on the basis of their: electronegativity atomic mass atomic number atomic size In the four major constituents of vitamin B complex, thiamine, riboflavin, pyridoxal and cynocobalamine: (p) riboflavin contains ribose sugar ; (q) thiamine contains pyridine ring ;(r) pyridoxal contains pyrimidine ring ; (s) cynacobalamine contains porphyrin ring The given statement is correct: r is true, s is false, p is true, q is false r is true, s is true, p is true, q is true r is false, s is true, p is false, q is false r is true, s is false, p is false, q is true 7. The thickness of tablets are measured by Sliding caliper scale Rotating disc technique Microscopic Technique Techincon Auto analyser 8. Hardness of tablet is measure by pfiser tester Strong Cobb Erweka tester All the above 9. The mesh size of USP disintegrator is 5-6 2.5 28-32 10 10. Aspartame has the main disadvantage as Carcinogenic Less sweeter than sucrose Hygroscopic in nature Bitter after taste Last edited by Neelurk; March 2nd, 2020 at 11:14 AM. |