The syllabus of M. Tech. Biotechnology (BBT) of VTU or Visvesvaraya Technological University on which the question paper is based is as follows:

MODULE 1: 10 HOURS
Introduction to statistics and study design: Introduction to statistics, data, variables, types of data, tabular, graphical and pictorial
representation of data. Significance of statistics to biological problems, experimental studies; randomized controlled studies, historically
controlled studies, cross over, factorial design, cluster design, randomized; complete, block, stratified design, biases, analysis and
interpretation.

MODULE 2: 10 HOURS
Descriptive statistics and Observational study design: Types of variables, measure of spread, logarithmic transformations, multivariate data.
Basics of study design, cohort studies, case-control studies, outcomes, odd ratio and relative risks.
Principles of statistical inference: Parameter estimation, hypothesis testing. Statistical inference on categorical variables; categorical data,
binomial distribution, normal distribution, sample size estimation

MODULE 3: 10 HOURS
Comparison of means: Test statistics; t-test, F distribution, independent and dependent sample comparison, Wilcoxon Signed Rank Test,
Wilcoxon-Mann-Whitney Test, ANOVA.
Correlation and simple linear regression: Introduction, Karl Pearson correlation coefficient, Spearman Rank correlation coefficient, simple
linear regression, regression model fit, inferences from the regression model, ANOVA tables for regression.
Multiple linear regression and linear models: Introduction, Multiple linear regression model, ANOVA table for multiple linear regression
model, assessing model fit, polynomials and interactions. One-way and Two-way ANOVA tables, F-tests. Algorithm and implementation
using numerical methods with case studies.

MODULE 4: 10 HOURS
Design and analysis of experiments: Random block design, multiple sources of variation, correlated data and random effects regression,
model fitting. Completely randomized design, stratified design. Biological study designs. Optimization strategies with case studies.

MODULE 5: 10 HOURS
Statistics in microarray, genome mapping and bioinformatics: Types of microarray, objectives of the study, experimental designs for micro
array studies, microarray analysis, interpretation, validation and microarray informatics. Genome mapping, discrete sequence matching,
programs for mapping sequences with case studies.

Attached Files

VTU M. Tech. Biotechnology Syllabus.pdf (244.2 KB, 153 views)